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Calamine Powder USP

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Calamine Powder USP, Safety Data Sheet


Calamine is a mixture of zinc oxide (ZnO) with about 0.5% iron(III) oxide (Fe2O3). It is the main ingredient in calamine lotion and is used as an antipruritic (anti-itching agent) to treat mild pruritic conditions such as sunburn, eczema, rashes, poison ivy, chickenpox, and insect bites and stings.

It is also used as a mild antiseptic to prevent infections that can be caused by scratching the affected area, and an astringent to dry weeping or oozing blisters and acne abscesses.In a September 2, 2008 document the U.S. Food and Drug Administration recommended applying topical OTC skin protectants, such as calamine, to relieve the itch caused by poisonous plants such as poison ivy, poison oak, and poison sumac.Calamine has been found to be effective in treating acne and poison ivy.


Other Names: N/A
Grade: USP
CAS: 8011-96-9
Appearance: Light Pink Powder
INCI Name: Calamine
Solubility: Insoluble
Natural or Synthetic: Natural, mix of Minerals.
Recommended Retest or Shelf Life:
Storage: Cool Dark Dry, Tightly Closed.


Not for Ingestion.In a 1992 press release, the U.S. Food and Drug Administration announced that no proof had been submitted showing the main ingredients in calamine (zinc oxide and iron(III) oxide) to be safe for use or effective in treating bug bites, stings, and rashes from poison ivy, poison oak, and poison sumac. The press release listed a total of 415 OTC drug ingredients which the FDA proposed banning for specific uses which are as yet unproven.

Safety Data Sheet (Calamine-Powder-USP.pdf, 110 Kb) [Download]

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